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Jobs/Modeling Engineer/Scientist (Contract-to-Hire)
Fulcrum Neuroscience, Inc.

Modeling Engineer/Scientist (Contract-to-Hire)

Fulcrum Neuroscience, Inc.

South San Francisco, California, United StatesContract0-2 yearsHybrid
Posted 1 week ago· America/Los_Angeles· South San Francisco, California, United States

Why This Is a Good Vibe Coding Job

Why This Is a Good Vibe Coding Job: Fulcrum Neuroscience is one of the few biotech firms explicitly seeking 'vibe coding' expertise and agentic workflow skills. This position allows you to move beyond manual entry by using AI-driven platforms to architect complex mechanistic models and create the tools that drive medical discovery.

The Future of Biotech Modeling

Fulcrum is building a world-class simulation engine to map brain health and combat neurodegeneration. As a Modeling Engineer, you will contribute to a 'digital twin' platform that uses causal logic and feedback loops to predict how Alzheimer’s progresses. This isn't just about data fitting; it’s about architecting a living repository of biological intelligence.

A First-Class Vibe Coding Role

What sets this role apart is the company’s forward-thinking approach to development. They are specifically looking for experts who use AI-assisted coding and agentic workflows to build complex systems. You will bridge the gap between high-level science and rapid engineering by using tools like Mathematica and custom AI interfaces to accelerate the modeling process.

Impact and Career Growth

  • Pioneering Tech: Shape a first-of-its-kind mechanistic model of the human brain.
  • Professional Recognition: Gain co-authorship on scientific publications and collaborate with industry leaders.
  • Career Path: Start with a high-impact contract role designed to transition into a permanent position with early-stage equity.

Education

  • postgraduate degree

Benefits

Early-stage equityCo-authorship on publications

Skills & Tags

Systems biologyComputational biologyODE-based modelingApplied AINonlinear systemsQuantitative systems pharmacologyBayesian inferenceMathematicaScientific communicationBiomedical engineeringChemical engineeringApplied mathematicsAI-assisted codingAgentic workflowsNeurodegenerationBrain physiology

Keywords

Modeling EngineerComputational BiologySystems BiologyNeuroscienceBiotechODE-based modelsNonlinear systemsApplied AIQuantitative Systems PharmacologyBayesian inferenceMathematicaAI-assisted codingAgentic workflowsMechanistic modelingDigital twinBiomarker patternsNeurodegenerationBrain homeostasisCausal representationData science

Categories

Science & ResearchEngineeringTechnologyHealthcareData & Analytics

Listing transparency: Job facts are based on the original employer or job-source listing. GoodVibeCode may use AI assistance to summarize and structure the description, followed by editorial checks.

Source: breezy

Last reviewed: Aug 21, 2026. How we source and review jobs.