Sr. Software Engineer (Contract-to-Hire)

Help Cure Alzheimer’s with Agentic AI

Fulcrum Neuroscience is looking for a software architect to help build a 'digital twin' of the human brain. In this role, you’ll move beyond traditional development by creating AI-driven tools that help scientists explore new therapies for neurodegenerative diseases. You will be a key player in an early-stage startup environment, turning complex biological data into interactive, agent-led discovery platforms.

The Vibe Coding Edge

This position is tailor-made for developers who have mastered frontier models and AI-assisted workflows. You will focus on:

• Agentic Architectures: Building systems that can perform autonomous research and goal-seeking tasks.
• MCP & LLM Integration: Implementing Model Context Protocol and RAG to connect vast scientific literature with large language models.
• Modern Tooling: Using AI-driven development to navigate complex Python codebases involving non-linear differential equations and Bayesian statistics.

Why Join?

As a contract-to-hire engineer reporting directly to the CTO, you’ll work at the intersection of high-level AI orchestration and deep-tech biotech. This is a rare opportunity to apply your vibe coding skills to mission-critical research while helping define the future of AI-enabled scientific discovery.